If you have the home office and spend long hours sitting is necessary that you have an organized space, as does the disorder affects our mood is somewhat exaggerated though it may seem real, because if you work in an environment where everything is you probably feel exhausted disordered and stressed, it is clear that some people are more sensitive than others, but this factor influences the way in anyone.
If you do not have a room that is exclusively used for the office you can use any section of the house that is available to locate the desktop, remember to achieve harmony in the whole place and that external factors are very important.